Tech platform

Extracellular vesicles are bioactive nanoparticles released by all kinds of cells. They are composed of several molecules, including lipids, proteins, and nucleic acids. Extracellular vesicles act as messengers between cells, transferring bioactive molecules from donor cells to recipient cells and modulating cell behavior.
Extracellular vesicles derived from plants represent a new emerging technology with several advantages. They can be manufactured using a scalable extractive method that produces concentrated preparations of extracellular vesicles. Moreover, plant extracellular vesicles can be easily administered using almost all routes (enteral, parenteral, and intranasal).
Pipeline
Plant extracellular vesicles show extraordinary features which make them attractive as an innovative solution for human therapy. We are developing new therapeutic solutions by exploiting different properties of extracellular vesicles, mainly focused on two therapeutic areas: wound care and drug delivery.

Thanks to our extensive experience in the field of regenerative medicine, we discovered the therapeutical properties of plant extracellular vesicles, making them a perfect adjuvant for wound care medications. This technology allows us to create a new generation of advanced therapies for wound care. EvoBiotech’s solution improves the outcome for patients and meets the need of healthcare professionals
Plant extracellular vesicles can improve numerous features essential for wound care advanced products, including:
As the first product in the pipeline, we are developing a hydrogel-based dressing to deliver plant extracellular vesicles on the site of lesion.

Our technology platform allows the development of a product pipeline for wound care with different formulations. The combination of plant extracellular vesicles with existing medications increases their regenerative effect for several clinical applications. The use of plant extracellular vesicles with different matrices allows the treatment of different types of wounds (exuding and not-exuding), whereas the formulation as eye drops improves the treatment of eye diseases. Moreover, the addiction of plant extracellular vesicles to sutures and ointmen improves their efficacy and promotes surgical wound and dermatitis healing.
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HYDROGEL +
EXTRACELLULAR
VESICLESNON-exuding wounds
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COLLAGEN +
EXTRACELLULAR
VESICLESExuding wounds
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EYE DROPS +
EXTRACELLULAR
VESICLESKeratitis, dry eye
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SUTURE +
EXTRACELLULAR
VESICLESSurgical wound
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OINTMENT +
EXTRACELLULAR
VESICLESDermatitis
Thanks to our extensive experience in the field of regenerative medicine, we discovered the therapeutical properties of plant extracellular vesicles, making them a perfect adjuvant for wound care medications. This technology allows us to create a new generation of advanced therapies for wound care. EvoBiotech’s solution improves the outcome for patients and meets the need of healthcare professionals.
Plant extracellular vesicles can improve numerous features essential for wound care advanced products, including:

Several features of plant extracellular vesicles make them an attractive alternative to the delivery systems currently used.
Thanks to our expertise in loading methods of extracellular vesicles, we can combine every type of molecule with plant extracellular vesicles to improve its effectiveness. Moreover, our innovative proprietary method to engineer extracellular vesicles allows dynamic loading of less compatible molecules without reducing the extracellular vesicle’s structural integrity.
As the first product in the pipeline, we are developing a delivery system for mRNA-based vaccines orally administered and storable at room temperature. Our solution will overcome all problems connected with the cold-supply chain and the medically-assisted administration. Moreover, it will provide easier access and a more comfortable vaccination experience for patients.
